Custom-made mouthguards may reduce risk of mild brain injury, study shows according to the June 2014 edition of The Journal of the American Dental Association, "Custom-made, pressure-laminated mouthguards might provide better protection from a mild traumatic brain injury (MTBI) / concussion injury than do over the counter mouthguards, according to a study published in the May/June issue of General Dentistry. The researchers followed 412 players from 6 high school football teams during the 2005 season. They randomly assigned 220 athletes from three teams to wear custom-made, pressure-laminated mouthguards, and 192 athletes from three teams to wear standard OTC mouthguards of their own choosing. All players wore the same football helmet during the study.

At the beginning of the study, the average thickness of the custom-made mouthguards in the posterier occlusal area was 3.5 millimeters and the average thickness of the OTC mouthguards was 1.65 mm, the authors wrote.

Each of a total of 23 athletes was identified as having had a MTBI/concussion injury during the football season, and one of these players had a second injury, the authors wrote. Fourteen of these athletes wore OTC mouthguards and two did not wear mouthguards at the time of the injury, for an incidence of 8.3 percent. Eight players in the custom-made mouthguard group experienced MTBI/concussion injuries, for an incidence of 3.6 percent."

"Although more research on this topic is needed, our study [results] show the value of a custom -made mouthguard," said Dr. Jackson Winters, a study coauthor and dentist in private practice in Findlay, Ohio"